| 09/01/05 | at | Towson | 26-29 |
| 09/10/05 | hosting | Bowie St | 21-35 |
| 09/17/05 | vs. | Savannah State | 55-26 |
| 09/24/05 | vs. | Hampton | 14-44 |
| 10/01/05 | at | Bethune-Cookman | 26-44 |
| 10/08/05 | vs. | North Carolina A&T | 33-40 |
| 10/15/05 | hosting | Howard | 7-0 |
| 10/22/05 | at | Delaware St | 14-41 |
| 10/29/05 | hosting | Florida A&M | 16-27 |
| 11/05/05 | hosting | Norfolk St | 21-24 |
| 11/10/05 | at | South Carolina St | 15-65 |