| 09/05/05 | vs. | North Carolina Central | 22-23 |
| 09/10/05 | hosting | Norfolk St | 16-14 |
| 09/15/05 | hosting | Hampton | 14-31 |
| 09/24/05 | at | Elon | 9-12 |
| 10/01/05 | vs. | Tennessee State | 16-3 |
| 10/08/05 | vs. | Morgan State | 40-33 |
| 10/15/05 | hosting | Delaware St | 13-23 |
| 10/22/05 | at | Howard | 0-16 |
| 10/29/05 | hosting | Bethune-Cookman | 17-54 |
| 11/05/05 | at | Florida A&M | 14-24 |
| 11/19/05 | vs. | South Carolina St | 27-43 |