| 09/10/05 | at | Gardner-Webb | 7-54 |
| 09/17/05 | at | Georgetown KY | 15-41 |
| 09/24/05 | at | Millsaps | 30-13 |
| 10/01/05 | at | Union KY | 33-44 |
| 10/08/05 | hosting | Shorter | 45-38 |
| 10/15/05 | hosting | Bethel TN | 28-31 |
| 10/22/05 | at | Lambuth | 18-35 |
| 10/29/05 | hosting | Campbellsville | 55-29 |
| 11/05/05 | hosting | Kentucky Wesleyan | 45-35 |
| 11/12/05 | at | Cumberland TN | 58-12 |
| 11/17/05 | at | Mississippi College | 16-52 |