| 08/27/05 | at | Charleston WV | 31-24 |
| 09/03/05 | hosting | SW Baptist | 29-34 |
| 09/10/05 | at | Geneva | 14-20 |
| 09/24/05 | hosting | Union KY | 29-14 |
| 10/01/05 | at | Georgetown KY | 29-30 |
| 10/08/05 | hosting | Cumberlands KY | 45-47 |
| 10/15/05 | at | Belhaven | 31-28 |
| 10/22/05 | at | Kentucky Wesleyan | 47-0 |
| 10/29/05 | hosting | Lambuth | 31-13 |
| 11/05/05 | hosting | Cumberland TN | 61-13 |
| 11/12/05 | at | Campbellsville | 51-19 |