| 09/02/06 | at | Missouri | 7-47 |
| 09/09/06 | at | Tennessee St | 15-25 |
| 09/16/06 | at | Indiana St | 59-40 |
| 09/23/06 | hosting | Illinois St | 14-35 |
| 09/30/06 | hosting | Tennessee Tech | 14-20 |
| 10/05/06 | at | Jacksonville St | 17-49 |
| 10/14/06 | hosting | Samford | 7-33 |
| 10/21/06 | at | Eastern Illinois | 10-20 |
| 10/28/06 | hosting | SE Missouri St | 17-24 |
| 11/04/06 | at | Eastern Kentucky | 21-51 |
| 11/18/06 | hosting | Tennessee-Martin | 14-42 |