| 09/03/05 | hosting | Alabama A&M | 14-27 |
| 09/10/05 | vs. | Jackson State | 20-14 |
| 09/17/05 | at | Tennessee-Martin | 20-42 |
| 09/24/05 | vs. | Florida A&M | 7-12 |
| 10/01/05 | vs. | North Carolina A&T | 3-16 |
| 10/13/05 | at | Tennessee Tech | 31-20 |
| 10/22/05 | hosting | Jacksonville State | 3-33 |
| 10/29/05 | at | Samford | 11-31 |
| 11/05/05 | hosting | Eastern Illinois | 3-27 |
| 11/12/05 | at | SE Missouri St | 24-32 |
| 11/19/05 | hosting | Eastern Kentucky | 0-49 |